Scientist 'E'

Preclinical Reprodutive and Genetic Toxicology
Phone : +(91-22) 2419-2022
Email  : vanageg@nirrh.res.in

Academic Background

Professional Experience

Research Interests

•  Reproductive Biology

•  Toxicology

•  Male Infertility.

Awards & Achievements

Post Doctoral Fellowships:

•  Melon Foundation, USA, 1990-1992

•  Fogarty International, USA , 2003-2004

Publications (Last 10)

1. Das B, Vanage G.R., Marshall A., Bardin C.W., and Koide S.S. Anti-Implantation activity of antiestrogens and mifepristone. Contraception, 54: 253-258, 1996.

2. Das, B., Vanage, G. R . , Li, X.J., Bardin, C.W. and Koide, S.S. Comparative effectiveness of three antiprogestins alone and incombination with Anordiol in terminating pregnancy in the rat. Contraception, 55:35-40, 1996.

3. Vanage, G.R. , Dao, B., Bardin, C.W., and Koide, S.S. Combination of antiestrogens and mifepristone for the termination of pregnancy in the rat. Res Comm Pharmac Toxicology 1:279-288, 1996.

4. Vanage G.R. , Mehta P.B., Moodbidri S.B., and Iyer K.S.N. (1999) Immunization with a synthetic peptide corresponding to region 1-17 of human seminal plasma inhibin: effect on fertility of male rats. Adv Reprod 3: 93-95,1999.

5. Vanage G.R. , Mehta P.B., Moodbidri S.B. and Iyer K S.N. Effect of immunization with synthetic peptide corresponding to region 1-17 of human seminal plasma inhibin on fertility of male rats. Arch Androl 44: 11-21, 2000.

6. U.Natraj.P.Bhatt, G.Vanage and S.B.Moodbdri (2002) Over expression of monkey oviductal protein: Purification and Characterization of recombinant protein and its antibodies. Biol. Reprod.67:1897-1906, 2002.

7. Kim Y H, Jha KN, Vanage G , Farris E, Snow PL, Klotz K, Nabby-Hansen S,Flickinger CJ, and. Herr J C. Translation and assembly of CABYR coding region B in fibrous sheath and restriction of calcium binding to coding region A Dev Biol 289:367-371, 2005.

8. Westbrook V.A., Schoppee P.D., Vanage G.R ., Klotz K.L., Diekman A.B. Flickinger C.J., Coppola M.A., Herr J.C.
   Hominoid-Specific SPAN-XA/D genes demonstrate differential expression in individuals and protein localization to a distinct nuclear envelope domain during spermatid morphogenesis Mol Hum Reprod 12:703-716,2006.

9. Salian Smita, Tanvi Doshi, Vanage G.R. Effect of Neonatal Exposure to Bisphenol A on Ontogenic Expression Pattern of Sertoli Cell Junctional Proteins in Rats. J. Life Sciences 85 : 11-18, 2009.

10. More A. B., Chilgunde S. N., Kamble J. C., Patil P. S., Malshe V. C., Vanage G. R. Devarajan P. V. Polyethylene sebacate: genotoxicity, mutagenicity evaluation and application in periodontal drug delivery system. J. Pharmaceutical Sciences 2009 (Accepted)

Past Students

•  M.Sc Ms Seema Kadam

Projects

• Establishing of National facility for Preclinical Reproductive and Genetic Toxicology (Jointly supported by Department of science and Technology and Indian Council of Medical Research)

• An Integrated Approach to Assess Human Sperm Chromatin Status for Understanding its Role in Male Fertility (Funded by Department of Biotechnology)