Scientist 'E'

Preclinical Reprodutive and Genetic Toxicology
Phone : +(91-22) 2419-2022
Email  : vanageg@nirrh.res.in

Academic Background

Professional Experience

Research Interests

•  Reproductive Biology

•  Toxicology

•  Male Infertility.

Awards & Achievements

Post Doctoral Fellowships:

•  Melon Foundation, USA, 1990-1992

•  Fogarty International, USA , 2003-2004

Publications (Last 10)

1. Salian S, Doshi T, Vanage G (2009) Impairment in protein expression profile of testicular steroid receptor coregulators in male rat offspring perinataly exposed to to Bisphenol A. Life Sciences 85 : 11-18

2. Salian S, Doshi T, Vanage G. (2009) Perinatal exposure of rats to Bisphenol A affects fertility of male offspring. Life sciences 88:742-752

3. More A.B., Chilgunde S.N., Kamble J.C., Patil P.S., Malshe V.C., Vanage G., Devarajan P.V. (2009). Polyethylene sebacate: genotoxicity, mutagenicity evaluation and application in periodontal drug delivery system. J. Pharmaceutical Sciences 98:4781-4795

4. Salian S, Doshi T, Vanage G. (2010). Perinatal exposure of rats to Bisphenol A affects fertility of male offspring – An Overview. Reprod. Toxicol. 31(3) : 359-362.

5. Salian S, Doshi T, Vanage G. (2010).Bisphenol-A affects male rat fertility for generations. Life Sciences Environmental Health News, 1-3, 2010

6. Dandekar PP, Jain R, Patil S, Dhumal R, Tiwari D, Sharma S, Vanage G, Patravale V. (2010). Curcumin Loaded Hydrogel Nanoparticles: Application in Anti- Malarial Therapy and Toxicological Evaluation. J.Pharmaceut. Sciences 99(12):4992-5010

7. Dandekar PP, Jain R, Dhumal R, Tiwari D, Vanage G, Patravale V. (2010). Toxicological evaluation of pH-sensitive nanoparticles of Curcumin : Acute, sub-acute and genotoxicity studies. Food Chemical Toxicol. 48(8-9):2073-89

8. Kurundkar SB, Sachan N, Kadam KM, Kulkarni VM, Bodhankar SL, D'Souza S, Vanage G, Ghole VS. (2010) Novel biphenyl compound, VMNS2e, ameliorates streptozotocin induced diabetic nephropathy in rats. J. Diabetes 2(4): 282-289

9. Doshi T, Salian S , Dighe V , Balasinor N, Vanage G. (2011). Hypermethylation of Estrogen Receptor Promoter Region in Adult Testis of Rats Exposed Neonatally to Bisphenol A. Toxicology. 289: 74-82

10. Dhumal R, Soni M, Devarajan P, Samad A, Gaikwad R, Vanage G. (2011) Evaluation of safety of lipomer doxycycline hydrochloride (Lipomer DH). J Biomed. Nanotechnol. 7: 146-147

Past Students

•  M.Sc Ms Seema Kadam

Projects

• Establishing of National facility for Preclinical Reproductive and Genetic Toxicology (Jointly supported by Department of science and Technology and Indian Council of Medical Research)

• An Integrated Approach to Assess Human Sperm Chromatin Status for Understanding its Role in Male Fertility (Funded by Department of Biotechnology)