Dr. Susan Thomas



Scientific
Technical
Administrative

 

 

 

 

 

 

 

 

Scientist 'B'

Biomedical Informatics Centre
Phone : +( 91-22) 2419 2104
Email  : thomass@nirrh.res.in


Academic Background

  • M.Sc. Tamil Nadu Agricultural University (Biotechnology; 1998)
  • Ph.D Indian Institute of Technology , Bombay (Biotechnology; 2007)


Professional Experience

Scientist NIRRH 2006 - Till date

 


Research Interests

  • Computational Biology

  • Drug design

  • Machine Learning Algorithms


Awards & Achievements

  • Best Ph.D Thesis Award IIT Bombay 2007

  • Finn World Travel Awardee 2006


Publications (Last 10)

  1. Sonawani, A., Nilawe, P., Barai, R.S., Idicula-Thomas, S. (2010) ClotBase: A knowledgebase on proteins involved in blood coagulation. Blood (Accepted)

  2. Mota, L., Shetty, S., Idicula-Thomas, S., Ghosh, K. (2010) Molecular analysis of hereditary factor X (FX) deficiency cases from Western India . Haemophilia PMID: 20331754

  3. Thomas, S., Karnik, S., Barai, R.S., Jayaraman, V.K., Idicula-Thomas, S. (2010) CAMP: a useful resource for research on antimicrobial peptides. Nucleic Acids Res. 38 (Database issue): D774-80.

  4. Mota, L., Shetty, S., Idicula-Thomas, S., Ghosh, K. (2009) Phenotypic and genotypic characterization of Factor VII deficiency patients from Western India . Clin Chim Acta. 409: 106-111.

  5. Dubey, S., Idicula-Thomas, S., Anwaruddin, M., Saravanan, C. Varma, R. Maitra, A. (2009) A novel 9-bp insertion detected in steroid 21-hydroxylase gene (CYP21A2): prediction of its structural and functional implications by computational methods. J Biomed Sci. 16:3

  6. Pai, N., Shetty, S., Idicula-Thomas, S., Kulkarni, B., Ghosh, K. (2009) Hereditary basis of protein C deficiency (PCD) in thrombosis patients: first report from India . Thromb Haemost 101:785-787

  7. Idicula-Thomas,S., Balaji, P.V. (2007) Correlation between the structural stability and aggregation propensity of proteins. In Silico Biol 7:225-237.

  8. Idicula-Thomas , S., Balaji, P.V. (2007) Protein aggregation: a perspective from amyloid and inclusion body formation. Curr. Sci. 92: 758-767.

  9. Idicula-Thomas, S., Kulkarni, A.J., Kulkarni, B.D., Jayaraman, V.K., Balaji, P.V. (2006) A support vector machine-based method for predicting the propensity of a protein to be soluble or to form inclusion body on over-expression in Escherichia coli. Bioinformatics 22: 278-284.

  10. Idicula-Thomas , S., Balaji, P.V. (2005) Understanding the relationship between the primary structure of proteins and their amyloidogenic propensity: clues from inclusion body formation. Prot. Eng. Des. Sel . 18: 175-180.

Projects

  • Elucidation of the role of primary structure of proteins on their antimicrobial activity (Funded by Department of Science and Technology)
  • Introduction of electronic patient record systems in Indian government hospitals (Funded by Department of Science and Technology)