Dr. Manjeet Kaur Sharma (nee Gill)



Scientific
Technical
Administrative

 

 

 

 

 

 

 

Scientist 'E'

Neuroendocrinology
Phone : +(91-22) 2419-2024
Email  : sharmam@nirrh.res.in

Academic Background

  • B.Sc. Hons . Panjab University , Chandigarh (Biochemistry ; 1966-69)
  • M.Sc. Hons. Panjab University , Chandigarh (Biochemistry ; 1969-71)
  • Doctorat d’Université Université Louis Pasteur CNRS, Strasbourg France (Neurochemistry ;1973-78)

Professional Experience

Scientist NIRRH 1979-Till Date

Research Interests

  • Molecular mechanisms underlying the regulation of spermatogenesis by reproductive hormones in rodent models.

  • Gene knockout to understand the molecular mechanisms underlying spermatogenesis in mouse models.

  • Understanding male infertility

  • Gain insights into testicular factors involved in the induction of chromatin damage

Awards & Achievements

  • National Merit Scholarship: 1969-1971

  • French Govt. Fellowship for higher studies: 1972-1978

  • Fogarty Fellowship (NIH): 2004-2005

Publications (Last 10)

  1. Aleem, M, Padwal V, Choudhari J, Balasinor N and Gill-Sharma M. K. Sperm protamine levels as indicators of fertilising potential in sexually mature male rats. Andrologia. 40(1):29-37, 2008.

  2. Gill-Sharma MK, Aleem M, Sethi G, Choudhari J, Padwal V, D’ Souza S, Balasinor N, Parte P, Juneja HS. Antifertility effects of fluphenazine in adult male rat. J Endocrinol Investig 26: 316-326 (2003).

  3. Betrabet SS, Choudhari J, Gill-Sharma MK. Use of viral promoters in mammalian based bioassays: How reliable? J Translational Med 2; 1-6 (2004).

  4. Kedia N, Gill-Sharma MK, Parte P, Juneja HS, Balasinor N. Effect of paternal tamoxifen on the expression of Insulin-like growth factor 2 and Insulin-like growth factor type 1receptor in the post-implantation rat embryos. Mol Reprod Dev 69(1): 22-30 (2004).

  5. Aleem M, Choudhari J, Padwal V, Balasinor N, Parte P, Gill-Sharma MK. Hyperprolactinemia affects spermiogenesis in adult male rats. J Endocrinol Investig 28(1): 39-48 (2005).

  6. Aleem M, Padwal V, Choudhari J, Balasinor N, Parte P, Gill-Sharma MK. Tamoxifen affects expression of transition proteins and protamine genes in adult rats adversely influencing the sperm DNA condensation. Asian J Androl 7(3): 311-321 (2005).

  7. Aleem M, Padwal V, Choudhari J, Balasinor N, Parte P, Gill-Sharma MK. Cyproterone acetate affects protamine gene expression in the testis of adult male rat. Contraception 71(5): 379-391 (2005).

  8. Choudhary J, Aleem M, Das-Gupta P, Padwal V, D’Souza R, Pathak S, Balasinor N, Gill-Sharma MK. The effects of estradiol on the expression of cytoskeletal proteins during spermatogenesis in the testis of sexually mature rats. Ind J Exp Biol 43(11): 1068-1079 (2005).

  9. D’Souza RD, Gill-Sharma MK, Pathak S, Kedia N, Kumar R, Balasinor N. Effect of high intratesticular estrogen on the seminiferous epithelium in adult male rats. Mol Cell Endocrinol 241: 41-48 (2005).

  10. Aleem M, Padwal P, Choudhari J, Balasinor N, Parte P, Gill-Sharma MK. Estradiol affects Androgen Binding Protein expression in the testis of adult male rat. Mol Cell Endocrinol 253: 1-13 (2006).

Past student

  • Dr. Muktar Aleem Ansari