Head, Dept of Gamete Immunobiology
Phone : +(91-22) 2419-2005
Email : email@example.com ; firstname.lastname@example.org
- M.Sc. University of Mumbai (Applied Biology; 1992)
- M.Sc University of Edinburgh , Scotland , U.K. (Reproductive Biology; 1996)
- Ph.D. University of Mumbai , (Biochemistry; 2000)
- Post Doc University of Massachusetts, Worcester (Biochem & Mol. Pharmacol.; 2003-2004)
||2012 - till date
- Cell Motility
- Reproductive Biology
Awards & Achievements
- Two years training fellowship at the Centre for Reproductive Biology of the University of Edinburgh, Scotland, U.K., under the financial support of the Rockefeller Foundation from Oct 1994 – Sept 1996.
- ‘Best Young ESI Presenter’ award for Oral Presentation for the paper entitled “Temporal effect of tamoxifen on testicular cytochrome P450 gene expression and steroid concentration in adult male rats.” Presented at the 31st National Conference of Endocrine Society of India, 9–11 December, 2001.
- NIH Postdoctoral fellowship under the supervision of Professor David Kupfer, Dept of Biochemistry and Molecular Pharmcology at the UMASS Medical School at Worcester, MA from May, 2003 to May 2004.
- Six week training fellowship for the special topics course in “Frontiers in Reproduction” at Marine Biological Laboratories, Woods Hole, MA, from 5th May 17th June, 2007.
- Best Poster award for the work entitled ‘Sperm Phosphoproteome Profiling by DIGE / LCMSE Reveals Altered Proteomic Signature in Asthenozoospermatozoa’ presented at the IPCON Conference on ‘Trends in Translational Proteomics’ held in New Delhi Proteomic Society of India from 3rd to 5th April, 2011.
- Winner of the Royan 16th International Research Award in the field of Embryology for research done entitled as “Tubulin Reversible Acetylation – Driving the Moves and the Moves behind the Drive” on September 2, 2015 in Razi Conference Center, Tehran, Iran. Royan Institute, Tehran, Iran - 2nd Sept 2015
- Awards by students
- Best poster award: Vivian Lobo – Title ‘Glucose Regulated Protein 78 : Chaperoning sperm motility?’ at the International conference on Reproductive Health: Issues and Strategies under Changing Climate Scenario and 24th Annual Meeting of Indian Society for the Study of Reproduction and Fertility held at Indian Veterinary Research Institute, Izatnagar, UP, INDIA from 6-8 February,2014.
- Oral Presentation (Third prize): Sweta Parab – Title ‘HDAC6 deacetylates alpha tubulin in sperm and modulates sperm motility’ at the 10th National Research Scholars Meet in Life Sciences-2014 held at ACTREC, Navi Mumbai 18-19th Dec 2014.
- Best poster award: Vivian Lobo - Title ‘Dynamics Of Glucose Regulated Protein 78 phosphorylation in sperm during epididymal maturation’. Society for Biological Chemists” held at NIRRH, Mumbai in August 2015.
Most recent publications
- Priyanka P Parte, Parimala Rao, Shweta Redij, Vivian Lobo, Serena J. D’Souza, Rahul Gajbhiye, Vijay Kulkarni Sperm Phosphoproteome profiling by Ultra Performance Liquid Chromatography followed by data independent analysis (LC-MSE) reveals altered proteomic signatures in Asthenozoospermia. Journal of Proteomics 75: 5861-5871, 2012.
- Rahul D Upadhyay, N H Balasinor, Anita V Kumar, Geetanjali Sachdeva, Priyanka P Parte, Kushaan Dumasia. Proteomics in reproductive biology: Beacon for unraveling the molecular complexities. BBA - Proteins and Proteomics 1834: 8 – 15, 2013.
- Shweta Bhagwat, Veena Dalvi, Darshan Chandrasekhar, Tinsu Matthew, Kshitish Acharya, Rahul Gajbhiye, Vijay Kulkarni, Shobha Sonawane, Manish Ghosalkar, Priyanka Parte. Acetylated alpha tubulin is reduced in individuals with poor sperm motility. Fertility & Sterility Jan;101(1):95-104, 2014.
- Sweta Parab, Omshree Shetty, Reshma Gaonkar, Nafisa Balasinor, Vrinda Khole, Priyanka Parte. HDAC6 deacetylates alpha tubulin in sperm and modulates sperm motility in Holtzman rat. Cell & Tissue Research, 359: 665-678, 2015.
- Bhavna Daswani, Manoj Kumar Gupta, Shubhangi Gavali, Meena Desai, Gajanan J Sathe, Anushree Patil, Priyanka ParteRavi Sirdeshmukh and M. Ikram Khatkhatay. Monocyte proteomics reveals involvement of phosphorylated HSP27 in pathogenesis of osteoporosis. Disease Markers, Volume 2015, Article ID 196589, http://dx.doi.org/10.1155/2015/196589
- Lobo V, Rao P, Gajbhiye R, Kulkarni V, Priyanka Parte. Glucose Regulated Protein 78 phosphorylation in sperm undergoes dynamic changes during maturation. Plos One 2015 DOI: 10.1371/journal.pone.0141858
- Sweta Parab
- Vivian Lobo
- Pratibha Varma
- Veena Dalvi
- Shweta Bhagwat*
- Aniket Patankar
Projects completed/ Ongoing as Principal Investigator
- Investigation of functional sperm proteins relevant to motility using the proteomics and in silico approach (Dept of Biotechnology; Completed).
- Role of HDAC6 and Cdyl gene in sperm motility (Dept of Science and Technology / ICMR; Completed)
- Characterization of the tubulin interactome involved in the orchestration of sperm flagellar motility (Dept of Biotechnology/ICMR; Completed)
- Defining the role of Glucose Regulated Protein 78 (GRP78) in Sperm Motility (Dept of Biotechnology; Ongoing)
- A study deciphering the role of HDAC6 in spermatogenesis. Ongoing
- Microtubule (MT) dynamics and sperm function: involvement of tubulin acetylation/deacetylation. Ongoing
- Development of a microfluidic device for good quality sperm selection for Assisted Reproductive Technologies (ART) Ongoing