Dr. Priyanka Parte



 

 

 

 

 

 

 

Scientist 'C'

Gamete Immunobiology
Phone : +(91-22) 2419-2006
Email  : partep@nirrh.res.in ; partep@icmr.org.in

Academic Background

  • M.Sc. University of Mumbai (Applied Biology; 1992)
  • M.Sc University of Edinburgh , Scotland , U.K. (Reproductive Biology; 1996)
  • Ph.D. University of Mumbai , (Biochemistry; 2000)

Professional Experience

Scientist B NIRRH 2002-2007
Scientist C NIRRH 2007-Till date

Research Interests

  • Cell Motility
  • Reproductive Biology
  • Proteomics

Awards & Achievements

  • Two years training fellowship at the Centre for Reproductive Biology of the University of Edinburgh, Scotland, U.K. , under the financial support of the Rockefeller Foundation from Oct 1994 – Sept 1996.

  • NIH Postdoctoral fellowship under the supervision of Professor David Kupfer, Dept of Biochemistry and Molecular Pharmcology at the UMASS Medical School at Worcester, MA from May, 2003 to May 2004.

  • Six week training fellowship for the special topics course in “Frontiers in Reproduction” at Marine Biological Laboratories, Woods Hole, MA, from 5 th May 17 th June, 2007 .

Publications (Last 10)

  1. Parte P , Balasinor N, Gill-Sharma MK, Maitra A and Juneja HS. Temporal effect of tamoxifen on cytochrome P450 side chain cleavage gene expression and steroid concentration in adult male rats. Journal of Steroid Biochemistry and Molecular Biology 82: 349-358, 2002.

  2. Balasinor N, Gill-Sharma MK, Parte P, D’Souza S, Kedia N and Juneja HS. Effect of paternal administration of an antiestrogen, tamoxifen, on embryo development in rats. Molecular and Cellular Endocrinology 190: 159-166, 2002.

  3. Kedia N, Gill-Sharma MK, Parte P, Juneja HS, Balasinor N. Effect of paternal tamoxifen on the expression of insulin-like growth factor 2 and insulin-like growth factor type 1 receptor in the post-implantation rat embryos. Mol Reprod Dev. 69(1):22-30, 2004.

  4. Aleem M, Choudhari J, Padwal V, Balasinor N, Parte P, Gill-Sharma MK. Hyperprolactinemia affects spermiogenesis in adult male rats. J Endocrinol Invest. Jan;28(1):39-48, 2005.

  5. Parte P and Kupfer D. Cyclic oxidation by human FMO1 and FMO3 of tamoxifen to tam-N-oxide and its reduction back to tamoxifen by human P450s: Model cyclic reactions for novel triphenylethyleneamine SERMs. Drug Metabolism and Disposition 33(10):1446-52, 2005.

  6. Aleem M, Padwal V, Choudhari J, Balasinor N, Parte P, Gill-Sharma M. Cyproterone acetate affects protamine gene expression in the testis of adult male rat. Contraception. 2005 May;71(5):379-91.

  7. Pires ES, Parte PP, Meherji PK, Khan SA, Khole VV. Naturally Occurring Anti Albumin Antibodies Are Responsible for False Positivity in Diagnosis of Autoimmune Premature Ovarian Failure. J Histochem Cytochem. 2006 54: 385-395.

  8. Aleem M, Padwal V, Chowdhari J, Balasinor N, Parte P, Gill-Sharma MK. Estradiol affects androgen binding protein expression and fertilizing ability of spermatozoa in adult male rats. Mol. Cell. Endocrinol. 253 (1-2): 1-13, 2006.

  9. Balasinor N, Parte P, Gill-Sharma MK, Kini J, Juneja HS. Mechanism delineating differential effect of an antiestrogen tamoxifen on the serum LH and FSH in adult male rats. J Endocrinol Invest. 29(6):485-496, 2006.

  10. Pathak S, Kedia-Mokashi N, Saxena M, D’Souza R, Maitra A, Parte P, Gill-Sharma MK and Balasinor N. Effect of tamoxifen treatment on global and Insulin-like growth factor 2-H19 locus specific DNA methylation in rat spermatozoa and its association with embryo loss. Fertility & Sterility: 91, (Supplement): 2253-2263, 2009

Present students

  • Parimala Rao
  • Sweta Parab

Projects

  • Investigation of functional sperm proteins relevant to motility using the proteomics and in silico approach.(Funded by Dept of Biotechnology)
  • Role of Histone DeAcetylase (HDAC6) and Cdyl gene in sperm motility. (Funded by Dept. of Science and Technology)