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Scientist 'C'
Gamete Immunobiology
Phone : +(91-22) 2419-2006
Email : partep@nirrh.res.in ; partep@icmr.org.in
Academic Background
- M.Sc. University of Mumbai (Applied Biology; 1992)
- M.Sc University of Edinburgh , Scotland , U.K. (Reproductive Biology; 1996)
- Ph.D. University of Mumbai , (Biochemistry; 2000)
Professional Experience
| Scientist B |
NIRRH |
2002-2007 |
| Scientist C |
NIRRH |
2007-Till date |
Research Interests
- Cell Motility
- Reproductive Biology
- Proteomics
Awards & Achievements
Two years training fellowship at the Centre for Reproductive Biology of the University of Edinburgh, Scotland, U.K. , under the financial support of the Rockefeller Foundation from Oct 1994 – Sept 1996.
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NIH Postdoctoral fellowship under the supervision of Professor David Kupfer, Dept of Biochemistry and Molecular Pharmcology at the UMASS Medical School at Worcester, MA from May, 2003 to May 2004.
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Six week training fellowship for the special topics course in “Frontiers in Reproduction” at Marine Biological Laboratories, Woods Hole, MA, from 5 th May 17 th June, 2007 .
Publications (Last 10)
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Parte P , Balasinor N, Gill-Sharma MK, Maitra A and Juneja HS. Temporal effect of tamoxifen on cytochrome P450 side chain cleavage gene expression and steroid concentration in adult male rats. Journal of Steroid Biochemistry and Molecular Biology 82: 349-358, 2002.
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Balasinor N, Gill-Sharma MK, Parte P, D’Souza S, Kedia N and Juneja HS. Effect of paternal administration of an antiestrogen, tamoxifen, on embryo development in rats. Molecular and Cellular Endocrinology 190: 159-166, 2002.
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Kedia N, Gill-Sharma MK, Parte P, Juneja HS, Balasinor N. Effect of paternal tamoxifen on the expression of insulin-like growth factor 2 and insulin-like growth factor type 1 receptor in the post-implantation rat embryos. Mol Reprod Dev. 69(1):22-30, 2004.
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Aleem M, Choudhari J, Padwal V, Balasinor N, Parte P, Gill-Sharma MK. Hyperprolactinemia affects spermiogenesis in adult male rats. J Endocrinol Invest. Jan;28(1):39-48, 2005.
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Parte P and Kupfer D. Cyclic oxidation by human FMO1 and FMO3 of tamoxifen to tam-N-oxide and its reduction back to tamoxifen by human P450s: Model cyclic reactions for novel triphenylethyleneamine SERMs. Drug Metabolism and Disposition 33(10):1446-52, 2005.
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Aleem M, Padwal V, Choudhari J, Balasinor N, Parte P, Gill-Sharma M. Cyproterone acetate affects protamine gene expression in the testis of adult male rat. Contraception. 2005 May;71(5):379-91.
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Pires ES, Parte PP, Meherji PK, Khan SA, Khole VV. Naturally Occurring Anti Albumin Antibodies Are Responsible for False Positivity in Diagnosis of Autoimmune Premature Ovarian Failure. J Histochem Cytochem. 2006 54: 385-395.
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Aleem M, Padwal V, Chowdhari J, Balasinor N, Parte P, Gill-Sharma MK. Estradiol affects androgen binding protein expression and fertilizing ability of spermatozoa in adult male rats. Mol. Cell. Endocrinol. 253 (1-2): 1-13, 2006.
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Balasinor N, Parte P, Gill-Sharma MK, Kini J, Juneja HS. Mechanism delineating differential effect of an antiestrogen tamoxifen on the serum LH and FSH in adult male rats. J Endocrinol Invest. 29(6):485-496, 2006.
- Pathak S, Kedia-Mokashi N, Saxena M, D’Souza R, Maitra A, Parte P, Gill-Sharma MK and Balasinor N. Effect of tamoxifen treatment on global and Insulin-like growth factor 2-H19 locus specific DNA methylation in rat spermatozoa and its association with embryo loss. Fertility & Sterility: 91, (Supplement): 2253-2263, 2009
Present students
Projects
- Investigation of functional sperm proteins relevant to motility using the proteomics and in silico approach.(Funded by Dept of Biotechnology)
- Role of Histone DeAcetylase (HDAC6) and Cdyl gene in sperm motility. (Funded by Dept. of Science and Technology)
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