Dr. Anurupa Maitra



Scientific
Technical
Administrative

 

 

 

 

 

 

Scientist 'E'

Molecular Endocrinology
Phone : +( 91-22) 2419 2009
Email  : maitraa@nirrh.res.in

Academic Background

  • M.Sc. University of Bombay (Biochemistry, 1972)
  • Ph.D. University of Bombay (Biochemistry, 1984)

Professional Experience

Research Scientist University of Virginia Health, Sciences Centre 1992-1993
Visiting Scientist ABC Life Technology Centre, Hamburg , Germany 2004-2005
Scientist NIRRH 1974- Till date

 

Research Interests

  • Reproductive Endocrinology
  • Molecular Genetics

Awards & Achievements

  • Awarded “Medical innovation” Grant by ICMR ( 2006-2007)
  • Awarded Indian National Science Academy Bilateral Exchange Grant for Germany (2004-2005)
  • Awarded Research Training grant ( 1992-1993) by the World Health Organization (WHO), for training in USA in the field of Molecular Biology
  • Awarded WHO Re-entry Grant (1995-1998 ) for studies on “Molecular Regulation of Steroidogenesis in Ovaries”.
  • Professor B.D. Tilak Visiting Fellowship Endowment (2007-2008) - University Institute of Chemical Technology, Mumbai.

Publications (Last 10)

  1. Pusalkar M, Meherji P, Gokral J, Chinnaraj S, Maitra A. CYP11A1 and CYP17 Promoter Polymorphisms Associate with Hyperandrogenemia in Polycystic Ovary Syndrome. Fertility Sterility.In Press – Available on-line

  2. Chatterjee S, Maitra A , Kadam S, Patel Z, Gokral J and Meherji P. CGG repeat sizing in the FMR1 gene in Indian women with premature ovarian failure  . Reproductive BioMedicine Online. - Accepted

  3. S.Mukherjee and A.Maitra. Molecular and genetic factors contributing to insulin resistance in polycystic ovary syndrome. Indian Journal of Medical Reseach - Accepted

  4. Singh N, Dubey S, Chinnaraj S, Golani A and Maitra A . Study of NAT2 gene polymorphisms in an Indian population: Their association with plasma isoniazid concentration in a cohort of tuberculosis patients. Molecular Diagnosis and Therapy 13 :1: 2009.

  5. Dubey S , Idicula-Thomas S, Anwaruddin M, Saravanan C, Varma RR and Anurupa Maitra A novel 9-bp insertion detected in steroid 21-hydroxylase gene (CYP21A2): prediction of its structural and functional implications by computational methods Journal of Biomedical Science 16 :3 : 2009.

  6. Pathak S, Kedia-Mokashi N, Saxena M, D’Souza R, Maitra A, Parte P, Gill Sharma M, Balasinor N.Effect of tamoxifen treatment on global and Insulin-like growth factor 2-H19 locus specific DNA methylation in rat spermatozoa and its association with embryo loss. Fertility and Sterility 9:5 : 2253-2263, 2009

  7. Mukherjee S, Shaikh N, Khavale S, Shinde G, Meherji P, Shah N, and Maitra A. G enetic variation in exon 17 of INSR is associated with insulin resistance and hyperandrogenemia among lean Indian women with polycystic ovary syndrome . Eur J Endocrinol.160 (5):855-62:2009.

  8. Sarkar C and Maitra A. Deciphering the cis-regulatory elements of co-expressed genes in PCOS by in silico analysis. Gene 408 : 72-84 , 2008

  9. Abid S, Maitra A, Gokral J, Meherji P, Pires E, Kadam S and Modi D. Altered expression of Progesterone recptor in infertile man. Reproductive BioMedicine Online 17 : 2, 2008

  10. Singh N, Golani A, Patel Z and Maitra A . Transfer of Isoniazid from circulation to breast milk in lactating women on chronic treatment for tuberculosis. British Journal of Clinical Pharmacology65: 418-422, 2008

Present students

  • Ms.Heena Shirwalkar
  • Ms.Madhavi Pusalkar
  • Ms. Shadaan Abid
  • Ms. Neera Singh
  • Mr. Chiradeep Sarkar

Past students

  • Ms.Vrushali Tanavde
  • Mr. Rahul Pingle

Projects

  • Genomic studies on polycystic Ovaries and Congenital Adrenal Hyperplasia (Funded by ICMR “Genomic” Fund)
  • Model to Predict Milk/Plasma ratios of therapeutic drugs (Funded by ICMR “Genomic” Fund)
  • Molecular characterization and nucleotide polymorphism (SNP) profiling in Congenital Adrenal Hyperplasia : A study with specific emphasis on steroid 21-Hydroxylase gene. (Funded by DST)
  • A genetic analysis of polycystic ovary syndrome with special emphasis on genes involved in insulin resistance (Funded by DST)
  • Development of a Rapid Molecular Technique for Diagnosis of Congenital Adrenal Hyperplasia due to Steroid 21-Hydroxylase Deficiency (ICMR Medical Innovation Fund)