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Scientist 'B'
National Center for Preclinical Reproductive and Genetic Toxicology
Phone: +91-22-
2419-2139
Email: dighev@nirrh.res.in
Academic Background
Professional Experience
Research Fellow |
National Biotechnology Center, Izatnagar-243 122, Uttar Pradesh |
Sept 1999 - Aug 2000 |
Research Associate |
National Professor Laboratory
Department of Veterinary Microbiology, CCS Haryana Agricultural University, Hisar, Haryana |
Sept 2000 – Sept 2001 |
Research Associate |
NATP Project, Department of Veterinary Microbiology, CCS Haryana Agricultural University, Hisar-125004, Haryana |
Oct 2001-March 2002 |
Research Associate |
ICMR Project , Microbial Containment Complex, National Institute of Virology, ICMR, Pune-411021, Maharashtra |
March 2002 - Jan 2003 |
Veterinary Officer |
Poultry Diagnostics Research Center of ‘Venkateshwara Hatcheries Group’ Pune, Maharashtra |
Feb 2003 - March 2003 |
Research Associate-II |
Lupin Research Park’ of Lupin LTD, Village Nande, Pune, Maharashtra |
March 2003 - Aug 2003 |
Scientist ‘B’ |
NIRRH |
August 2003-till date |
Research Interests
- Reproductive Biology
- Toxicology
- Bioinformatics
- Non- human Primate Experimental Medicine.
Awards & Achievements
- Overseas Training fellowship at Oregon National Primate Research Center (OHSU) Beaverton, Oregon USA, in the area of “Assisted Reproductive Technologies (ARTs) in non-human primates, Stem cell derivation and characterization, Epigenetic reprogramming of ES cells and Derivation of Specific pathogen free Monkey for biomedical research.
- Qualified ICAR-National Eligibility Test
- Awarded Indian Veterinary Research Institute-Junior Research Fellowship (1997-1999)
- Awarded Indian Council of Agriculture Research Merit Scholarship (1992-1997)
Publications (Last 10)
- Cohen NM, Dighe V, Landan G, Reynisdóttir S, Palsson A, Mitalipov S, Tanay A. DNA methylation
programming and reprogramming in primate embryonic stem cells. Genome Research; 19(12):2193-201, 2009.
- Sparman M, Dighe V, Sritanaudomchai H, Ma H, Ramsey C, Pedersen D, Clepper L, Nighot P, Wolf D, Hennebold J, Mitalipov S. Epigenetic Reprogramming by Somatic Cell Nuclear Transfer in Primates.
Stem Cells. 27(6):1255-1264, 2009.
- Dighe V, Clepper L, Pedersen D, Byrne J, Ferguson B, Gokhale S, Penedo MC, Wolf D, Mitalipov S.(2008). Heterozygous embryonic stem cell lines derived from nonhuman primate parthenotes.Stem Cells. 26(3):756-66
- Prabagaran E, Bandivdekar AH, Dighe V, Raghavan VP (2007). HOXBES2: A Novel Epididymal HOXB2 Homeoprotein and Its Domain-Specific Association with Spermatozoa. Biology of Reproduction . 76 (2):314-26.
- Dechamma HJ, Dighe V, Kumar CA, Singh RP, Jagadish M, Kumar S (2006). Identification of T-helper and linear B epitope in the hypervariable region of nucleocapsid protein of PPRV and its use in the development of specific antibodies to detect viral antigen. Veterinary Microbiology. 118 (3-4): 201-11.
- V.D. Dighe, Y.P. Grover and R. Pandey (2003). Epidemiological studies on bovine rotavirus in neonatal diarrhoeic calves at organized dairy farms in Haryana and adjoining areas using RNA-PAGE during the year 1997-2000 Indian Journal Animal Sciences 73 (6): 623-626.
- D.T. Mourya., M.S. Rohankhedkar., P. Yadav., V. Dighe, and D. N. Deobagkar (2003). Enhanced esterase activity in the salivary gland and midgut of Aedes aegypti mosquitoes infected with dengue-2 virus Indian Journal of Experimental Biology 41: 91-93.
- P.V. Barde , Rane S.R., Singh D.K. , Yadav P., Dighe V, Gokhale M.D., Mourya D.T.(2003) Concomitant effect of Bacillus thuringenesis H-14 toxin and atropine sulphate on the gut epithelium cells of female Aedes aegypti mosquitoes. Entomon Trivandrum 28(2): 161-163.
Projects
1) Human β-Microseminoprotein: Studies on structural characterization and understanding its role in modulation of Follicle Stimulating Hormone and sperm function (as Co-Investigator- Funded by Department of Biotechnology )
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