Dr. Meena Desai



 

 

 

 

 

 

 

Scientist 'C'

Molecular Immunodiagnostics
Phone : +( 91-22) 2419 2026
Email  : desaim@nirrh.res.in


Academic Background

Degree /Diploma

University

Year

Field of Study

PhD

NIRRH - University of Mumbai

1994

Biochemistry

MSc

Sir H. N. Hospital - University of Mumbai

1985

Applied Biology

Post Doctoral Fellow

Univ. Of Tennessee, USA

2007-2008

Molecular Sciences

Research Associate

Dept. of Biotechnology, Govt. of India

1994-1996

Biochemistry


Professional Experience

Sr No.

Name of the Institute

Designation

From

To

1.

NIRRH

Scientist C

2016

Till date

2.

NIRRH

Scientist B

2013

2016

3.

NIRRH

Scientist C (DST Project)*

2012

2013

4.

NIRRH

Scientist B (DFW Project)*

2008

2011


Research Interests


Biochemistry, Molecular Biology and Immunodiagnostics

  • Development of ELISAs for Reproductive Hormones and Bone turnover Markers

  • Production of Key Immuno reagents antisera and enzyme labels

  • Purification and Characterisation of antisera and Validation of assays

  • Molecular and Immune mechanisms regulating Osteoporosis


Awards & Achievements

  • Best oral presentation award for the paper entitled Implications of OPG, RANK and RANKLin the pathogenesis of postmenopausal osteoporosis. Association of Clinical Biochemists of India (ACBICON), Nov 25-28th,2015 Chandigarh.
  • Gold medal awarded for Major Achievements in the field of Biological Sciences by the American Biographical Inc, USA, 2001.
  • Best Poster Award for the paper entitled “Osteoprotegerin and RANKL: Relationship with BMD and markers of bone turnover in Indian women’ International Conference on Reproductive Health with Emphasis on Occupational, Environmental and Lifestyle Factors, 26TH Annual Meeting of ISSRF, Ahmedabad,18-20th Feb,2016
  • Best Paper Award for the paper entitled “Bone turnover markers, bone density and hormonal profiles across the menopausal transition” Symposium on Metabolic Bone Disorders, I st National Conference of Indian Society for Bone and Mineral Research, November 11 th – 14 th, 2005, New Delhi, India.
  • Best Scientific performance award presented by Hon Health Minister Dr. C. P. Thakur for the year 2001-2002, NIRRH, Mumbai, March, 2002.


Publications
(Last 10)

1Daswani B, Desai M, Mitra S, Gavali S, Patil A, Kukreja S, Khatkhatay MI. Influence of bone mineral density measurement on fracture risk assessment tool (FRAX®) scores in postmenopausal Indian women.Post Reprod Health 22: 20-24, 2016

2Bhavna Daswani, M K Gupta, S Gavali, M Desai, G J Sathe, A Patil, P Parte, R Sirdeshmukh, M I Khatkhatay Monocyte proteomics reveals involvement of phosphorylated HSP27 in pathogenesis of osteoporosis Disease Makers (Accepted ), March 2016

3 Bhavna Daswani, S Gavali, M Desai, A Patil, M I Khatkhatay Serum levels of phosphorylated HSP27 can indicate low BMD in premenopausal and postmenopausal Indian women IJMR Ind J Med Res: 143:288-296, 2016

4 Desai Meena, Motivaras Hetal and M.I. Khatkhatay Role of bone turnover markers in assessment of Osteoporosis: emerging trends Journal of Association of Medical Women of India, vol VII (1):19-22,2015

5 Deepa R. Mhatre , S. D. Mahale , M.I. Khatkhatay , S.S. Desai , D. D. Jagtap,J V. Dhabalia ,H B. Tongaonkare, Meena P. Desai , S. P. Dandekar , A.M. Varadkara Development of an ELISA for sPSP94 & utility of the sPSP94/sPSA ratio as a diagnostic indicator to differentiate between benign prostatic hyperplasia and prostate cancer .Clinica Chimica Acta, 436: 256-262, 2014

6 M.Ikram Khatkhatay and Meena Desai Genetic factors contributing to bone health:
Postmenopausal osteoporosis : Basic and Clinical concepts (ed; Meeta, Jay pee Bros, Medical Publishers, New Delhi, India):39-50, 2013

7 Meena Desai, MI Khatkhatay, VR Taskar, Z Ansari. Changes in Cytokines, Biomarkers of Bone Turnover and Hormones Are Associated With Bone Loss in Postmenopausal Indian Women. Int J Endocrinol Metab. 10: 399-403, 2012.

8 H A Abdelsamed, ,Meena Desai Stephanie Nance and Elizabeth Fitzpatrick T bet controls severity of hypersensitivity pneumonitis J of Inflammation 2011,8:8-15

9 Kalpana K. Venkat, Murli M. Arora, Parduman Singh, Meena Desai, MI Khatkhatay. Effect of alcohol consumption on BMD and hormonal parameters in physically active male soldiers. Bone 45:449-454, 2009

10 Kalpana Venkat, Meena Desai, M M Arora, P Singh, M Ikram Khatkhatay. Age-related changes in sex steroid levels influence BMD in healthy Indian men. Osteoporosis International, 20 (6): 955-962, 2009


Completed Projects

1 Preparation of a multi-analyte ELISA array of bone turnover markers for the assessment of bone health

2 Elucidating the differences in monocyte proteome from pre and postmenopausal women with varying bone mass


Ongoing Projects

S No.

Title of Project

Funding Agency

Date of sanction and Duration

1.

OPG,RANK,RANKL as new biomarkers for Osteoporosis

NIRRH

January,2013 Three years

2.

Elucidating the difference in the cellular proteome of monocytes from pre and post- menopausal women with varying bone mass (Co-Investigator)

BRNS

January 2012 Three years

3.

Preparation of a multianalyte ELISArray of bone turnover markers for the assessment of bone health. (Principal-Investigator)

DST

February 2012 Two years