Dr. Deepa Bhartiya



Scientific
Technical
Administrative

 

 

 

 

 

 

 

Scientist 'E'

Stem Cell Biology
Phone : +(91-22) 2419-2012
Email  : bhartiyad@nirrh.res.in ; deepa.bhartiya@yahoo.in

Academic Background

  • M.Sc. Punjab University , Patiala , (Zoology)
  • Ph.D. Central Drug Research Institute, Lucknow (Zoology)

 

Professional Experience

Post Doc Fellow Dept of Pathology, Uniformed Services University of Health Sciences, Bethesda , Maryland , USA
1989-1991
Fogarty Fellow Development Endocrinology Branch, National Inst. of Child and Development, National Inst of Health (NIH), Bethesda , Maryland , USA 1991-1994
Scientist Cell Biology Dept, BJ Wadia Hospital for Children, Mumbai
 1995- 2000
Scientist Genetics, Reliance Life Sciences Pvt. Ltd, Mumbai 2001- 2002
Scientist NIRRH
2003- Till Date
Visiting Scientist Three months Visiting Associateship (sponsored by DBT) for Training at Buck Institute, California, USA. 2008
Visiting Scientist Trained during a three day NIH sponsored ES Cell Course at Stem Cell Centre, University of Minnesota , MO , USA 2008

 

 

 

 

 

 




Research Interests

  • Pluripotent stem cells and Regenerative medicine
  • Fertility issues of cancer patients

Awards & Achievements

  • Best Poster award by Mr Neeraj Kumar at Bio-immunoregulatory Mechanisms Associated with Reproductive Organs: Relevance in Fertility and in Sexually Transmitted Infections, held at National Institute of Immunology, New Delhi, India from 9 th - 13 th February 2009
  • Prof Awatarkrishnan Award by Mr Prasad Pethe when he participated in the Workshop entitled “Hands-on Basic Flow Cytometry Course” organized jointly by C-CAMP and National Centre for Biological Sciences held at National Centre for Biological Sciences, Bangalore from 17 th – 21 st , 2009.
  • Pande-Rath Prize by Ms Sreepoorna Unni for participation in the Basic Flow Cytometry training course, conducted by The Cytometry Society of India, CDRI, Lucknow from 10 th – 13 th September, 2008.
  • Best Poster Award - during International Symposium: Advances and Challenges in Reproductive Health Research in the Post Genomic Era in 2005 at NIRRH, Mumbai
  • Best Poster Award - at the 11 th International Conference “Issues on Tissues” Asia Pacific Association of Surgical Tissue Banks, 24 th – 26 th November 2006, held at Tata Memorial Hospital, Mumbai.
  • Best Poster Award - at Bio-immunoregulatory Mechanisms Associated with Reproductive Organs: Relevance in Fertility and in Sexually Transmitted Infections, held at National Institute of Immunology, New Delhi, India from 9 th – 13 th February 2009.
  • Awarded Biotechnology Overseas Associateship by Dept. of Biotechnology, Government of India to train at Buck Institute, California, USA on Embryonic Stem Cells Differentiation and Genetic Manipulation, 2008.

Conferences / Training Workshops Organized

  • Helped organize Public Consultation for Western Region ICMR-DBT Guidelines for Stem Cell Research and Therapy (20 th Feb, 2010) at Nehru Science Centre, Worli, Mumbai
  • Brainstorming on Human Embryonic Stem Cells, 15 – 16 January, 2010 supported by DBT
  • Hands- on Workshop on Human Embryonic Stem Cells: Differentiation and Genetic Manipulation, 18 - 23 January, 2010 supported by DBT
  • Brainstorming meeting entitled “Oncofertility: Recent Advances Jointly Organized by Stem Cell Biology Department, NIRRH and Tata Memorial Centre on November 17, 2009
  • International Symposium on Stem Cells: Premises and Promises for Research and Therapeutics, 18-21 September 2005.
  • Application of Oocyte Maturation, Embryo Culture, Parthenogenesis and SCNT for Generation of Autologous Embryonic Stem Cells, DBT supported Training Course from November 26- December 7, 2007.
  • WHO sponsored In-Country Fellowship Training Course on Assisted Reproductive Technologies, 2005 and 2007.

Publications (Last 10)

  1. Bhartiya D, Shaikh A, Nagvenkar P, Sandhya K, Pethe P, Pawani H, Mohanty S, Rao SGA, Hinduja I and Zaveri K. Very small embryonic-like stem cells with maximum regenerative potential get discarded during cord blood banking and bone marrow processing for autologous stem cell therapy. Stem Cells and Dev (2011) [Epub ahead of print].

  2. Parte S, Bhartiya D, Daithankar V, Salvi V, Zaveri K, Hinduja I. Detection, characterization and spontaneous differentiation in vitro of very small embryonic-like putative stem cells in adult mammalian ovary. Stem Cells and Dev (2011) 20(8):1451-64.

  3. Nagvenkar P, Pethe P, Pawani H, Telang J, Kumar N, Hinduja I, Zaveri K, Bhartiya D. Evaluating differentiation propensity of in-house derived human embryonic stem cell lines KIND-1 and KIND-2. In Vitro Cell Dev Biol Anim. (2011) 47(5-6):406-19.

  4. Bhartiya D, Kasiviswanathan S, Unni SK, Pethe P, Dhabalia JV, Patwardhan S, Tongaonkar HB. Newer Insights Into Pre-meiotic Development of Germ Cells in Adult Human Testis Using Oct-4 as a Stem Cell Marker J Histochem Cytochem (2010) 58(12):1093-1106.

  5. Kumar N, Pethe P, Bhartiya D. Role of TGF beta and myofibroblasts in supporting the propagation of human embryonic stem cells in vitro. International Journal of Developmental Biology. (2010) 54:1329-1336.

  6. Nandedkar P, Chohan P, Patwardhan A, Gaikwad S, Bhartiya D. Parthenogenesis and somatic cell nuclear transfer in sheep oocytes using Polscope. Indian J Exp Biol. (2009) 47(7):550-558.

  7. Unni SK, Modi DN, Pathak SG, Dhabalia JV, Bhartiya D. Stage-specific localization and expression of c-kit in the adult human testis. J Histochem Cytochem. (2009) 57(9):861-869.

  8. Kumar N, Hinduja I, Nagvenkar P, Pillai L, Zaveri K, Mukadam L, Telang J, Desai S, Mangoli V, Mangoli R, Padgaonkar S, Kaur G, Puri C, Bhartiya D. Derivation and characterization of two genetically unique human embryonic stem cell lines on in-house-derived human feeders. Stem Cells Dev. (2009)18(3):435-445. 

Present students

Ms. Sreepoorna Unni

Ms Seema Parte

Mr Prasad Pethe

Ms Sandhya Kasiviswanathan

Ms Ambreen Shaikh

Past student

Ms Prajakta Berde (M.Sc.)

Ms Lata Shamale (M.Sc.)

Ms Chhaya Kapadia (Ph.D.)

Ms Shamim Sheikh (Ph.D.)

Ms Rajbinder Kaur (Ph.D.)

Mr Deepak Modi (Ph.D.)

Mr Neeraj Kumar (Ph.D.)

Woman Scientist (DST)

Dr Kalpana Sriraman

Projects

  • Differentiation and characterization of cardiac progenitor cells and early cardiomyocytes derived from indigenously developed human embryonic stem cell lines.
    Funded by Ministry of Science and Technology, Department of Biotechnology (Ongoing)

  • Derivation of additional human embryonic stem cell lines from spare and discarded embryos and their characterization.
    Funded by Ministry of Science and Technology, Department of Biotechnology (Ongoing)

  • Lineage specific differentiation of human embryonic stem cells into insulin producing cells.
    Funded by Ministry of Science and Technology, Department of Biotechnology (Ongoing)

  • Isolation and Propagation in vitro of VSELs from adult gonadal tissue and 3D maturation of germ cells.
    Funded by Ministry of Science and Technology, Department of Biotechnology (Ongoing)

  • Development of non-human primate (Marmoset) ES cells as a regenerative source for cell therapy.
    Funded by Ministry of Science and Technology, Department of Biotechnology (Completed)

  • To establish technologies of parthenogenesis and somatic cell nuclear transfer (SCNT) using sheep eggs.
    Funded by Ministry of Science and Technology, Department of Biotechnology (Completed)

  • To establish human embryonic stem (hES) cell lines without mouse feeder (MEF) layersand study factors in MEF layer that prevent differentiation of hES cells in Vitro.
    Funded by Ministry of Science and Technology, Department of Biotechnology (Completed)

  • To standardize protocols for cryopreservation of gonadal tissue and study follicle growth in SCID mice.
    Funded by DST, Ministry of Science and Technology, New Delhi (Completed)