Dr. Deepa Bhartiya



Scientific
Technical
Administrative

 

 

 

 

 

 

 

Scientist 'D'

Stem Cell Biology
Phone : +(91-22) 2419-2012
Email  : bhartiyad@nirrh.res.in

Academic Background

  • M.Sc. Punjab University , Patiala , (Zoology)
  • Ph.D. Central Drug Research Institute, Lucknow (Zoology)

 

Professional Experience

Visiting Fellow Dept of Pathology, Uniformed Services University of Health Sciences, Bethesda , Maryland , USA
1989-1991
Fogarty Fellow Development Endocrinology Branch, National Inst. of Child and Development, National Inst of Health (NIH), Bethesda , Maryland , USA 1991-1994
Scientist Cell Biology Dept, BJ Wadia Hospital for Children, Mumbai
 1995- 2000
Scientist Genetics, Reliance Life Sciences Pvt. Ltd, Mumbai 2001- 2002
Scientist NIRRH
2003- Till Date
Visiting Scientist Three months Visiting Associateship (sponsored by DBT) for Training at Buck Institute, California, USA. 2008
Visiting Scientist Trained during a three day NIH sponsored ES Cell Course at Stem Cell Centre, University of Minnesota , MO , USA 2008

 

 

 

 

 

 




Research Interests

  • Embyronic stem cells and Regenerative medicine
  • Gonadal tissue cryopreservation and fertility preservation

 

Awards & Achievements

  • Best Poster Award - during International Symposium: Advances and Challenges in Reproductive Health Research in the Post Genomic Era in 2005 at NIRRH, Mumbai
  • Best Poster Award - at the 11 th International Conference “Issues on Tissues” Asia Pacific Association of Surgical Tissue Banks, 24 th – 26 th November 2006, held at Tata Memorial Hospital , Mumbai.
  • Best Poster Award - at Bio-immunoregulatory Mechanisms Associated with Reproductive Organs: Relevance in Fertility and in Sexually Transmitted Infections, held at National Institute of Immunology, New Delhi, India from 9- 13 th February 2009.
  • Awarded Biotechnology Overseas Associateship by Dept. of Biotechnology, Government of India to train at Buck Institute, California, USA on Embryonic Stem Cells Differentiation and Genetic Manipulation.

Conferences / Training Workshops Organized

International Symposium on Stem Cells: Premises and Promises for Research and Therapeutics, 18-21 September 2005.

Application of Oocyte Maturation, Embryo Culture, Parthenogenesis and SCNT for Generation of Autologous Embryonic Stem Cells, DBT supported Training Course from November 26- December 7, 2007.

WHO sponsored In-Country Fellowship Training Course on Assisted Reproductive Technologies, 2005 and 2007.

Publications (Last 10)

  1. Lakshmi Pillai and Bhartiya D (2009) Stem Cell Matters of the Heart. Nature India(Published online)

  2. Unni S, Modi D, Pathak S, Dhabalia J and Bhartiya D. Stage - specific localization and expression of c-kit in the adult human testis. J Histochem and Cytochem (in press, 2009)

  3. Nandedkar P, Chohan P, Patwardhan A, Gaikwad S & Bhartiya D. Sheep parthenogenesis and somatic cell nuclear transfer using Polscope. Indian Journal of Experimental Biology 47, 550- 58, 2009.

  4. Kumar N, Hinduja I, Nagvenkar P, Pillai L, Agrawal P, Zaveri K, Mukadam L, Telang J, Desai S, Mangoli V, Mangoli R, Padgaonkar S, Kaur G, Puri C and Bhartiya D. Derivation and characterization of two genetically unique human embryonic stem cell lines on in-house derived human feeders. Stem Cells and Development, 18(3): 67-77, 2009.

  5. Bhartiya D, Ritchie W, Hinduja I, Nandedkar P, Zaveri K, Mukadam L, Chohan P, Patwardhan A, Nagvenkar P, Kumar N, Tat P, Richings N, Verma P. Human Somatic Cell Nuclear Transfer and Parthenogenesis: Preliminary Indian experience. Journal of Stem Cells 3(4): 255-264, 2008.

  6. Modi D, Bhartiya D. Y chromosome mosaicism and occurrence of gonadoblastoma in cases of turner syndrome or amenorrhoea (Published online 2007)

  7. Bhartiya D, Kumar N and Puri CP. Miracle Cell: The stem Cell.FOGSI Focus

  8. Modi D, Bhartiya D, Puri C. Developmental expression and cellular distribution of Mullerian inhibiting substance in the primate ovary. Reproduction.;132(3):443-53, 2006

  9. Bhartiya D, Kumar N, Stem Cells and their Therapeutic Potential Annals of National Academy of Medical Sciences, 41, 93- 102,2005.

  10. Modi D, Shah C, Sachdeva G, Gadkar S, Bhartiya D, Puri C. Ontogeny and cellular localization of SRY transcripts in the human testes and its detection in spermatozoa. Reproduction. 2005;130(5):603-13, 2005

Present students

Mr Neeraj Kumar

Ms. Sreepoorna Unni

Ms Seema Parte

Mr Prasad Pethe

Past student

Ms Prajakta Berde (M.Sc.)

Ms Lata Shamale (M.Sc.)

Ms Chhaya Kapadia (Ph.D.)

Ms Shamim Sheikh (Ph.D.)

Ms Rajbinder Kaur (Ph.D.)

Mr Deepak Modi (Ph.D.)

Projects

  • To establish human embryonic stem (hES) cell lines without mouse feeder (MEF) layers and study factors in MEF layer that prevent differentiation of hES cells in vitro (Funded by Department of Biotechnology (DBT))

  • Development of non-human primate (Marmoset) ES cells as a regenerative source for cell therapy (Funded by DBT)

  • To standardize protocols for cryopreservation of gonadal tissue and study follicle growth in SCID mice (Funded by DST)

  • Differentiation and characterization of cardiac progenitor cells and early cardiomyocytes derived from indigenously developed human embryonic stem cell lines (Funded by DBT)

  • To establish technologies of parthenogenesis and somatic cell nuclear transfer (SCNT) using sheep eggs (Funded by DBT)

  • Lineage specific differentiation of human embryonic stem cells into insulin producing cells (Funded by DBT)

  • Derivation of additional well characterized human embryonic stem (hES) cell lines from spare embryos and single blastomeres (Funded by DBT)