Dr. Nafisa Balasinor



 

 

 

 







 

Scientist 'D'

Neuroendocrinology
Phone : +( 91-22) 2419 2025
Email  : balasinorn@nirrh.res.in

Academic Background

  • M.Sc. Sophia College , University of Bombay (Life Sciences, 1982)
  • Ph.D. Institute for Research in Reproduction, University of Bombay (Biochemistry, 1989)

Professional Experience

Scientist NIRRH 1992-Till Date

 


Research Interests

  • Reproductive Neuroendocrinology
  • Epigenetics

Awards & Achievements

  • Awarded Overseas Research Associateship from Department of Biotechnology for training under Prof. Rex Hess, Department of Veterinary Biosciences, University of Illinois, USA. 2002-2003

Publications (Last 10)

  1. Kedia N, Gill-Sharma MK, Parte P, Juneja HS, Balasinor N. Effect of paternal tamoxifen on the expression of insulin-like growth factor 2 and insulin-like growth factor type 1 receptor in the post-implantation rat embryos. Mol. Reprod. Dev. 69:22–30 (2004).

  2. D’Souza R, Gill-Sharma MK, Pathak S, Kedia N, Kumar R and Balasinor N. Effect of high intratesticular estrogen on the seminiferous epithelium in adult male rats. Mol Cell Endocrinol. 28;241(1-2):41-8 (2005).

  3. Choudhuri J, Aleem M, Padwal V, Das Gupta P, D’Souza R, Pathak S, Balasinor N and Gill-Sharma MK. Effect of estradiol on expression of cytoskeletal proteins during spermatogenesis in testis of sexually mature rats. Indian J Exp Biol.;43(11):1068-79 (2005).

  4. Aleem M, Padwal V, Choudhari J, Balasinor N, Parte P and Gill-Sharma MK. Effects of tamoxifen citrate on gene expression during nuclear chromatin condensation in male rats. Asian J Androl.; 7(3):311-21 (2005).

  5. Aleem M, Padwal V, Choudhari J, Balasinor N, Parte P and Gill-Sharma MK. Cyproterone acetate affects protamine gene expression in the testis of adult male rat. Contraception;71(5):379-91 (2005).

  6. Aleem M, Choudhari J, Padwal V, Balasinor N, Parte P and Gill-Sharma MK. Hyperprolactinemia affects spermiogenesis in adult male rats. J Endocrinol Invest.; 28(1):39-48 (2005)

  7. Balasinor N , Parte P, Gill-Sharma MK, Kini J, Juneja HS Mechanism delineating differential effect of an antiestrogen, tamoxifen, on the serum LH and FSH in adult male rats. J Endocrinol Invest.; 29(6):485-96 (2006)

  8. Balasinor N, Bhan A, Paradkar N, Shaikh A, Nandedkar T, Bhutani K.K., Roy Chaudhury M. Post natal development and reproductive performance of F1 progeny exposed in-utero to an ayurvedic contraceptive: Pippaliyadi yoga. Journal of Ethnopharmacology ; 109(3):406-11 (2007)

  9. Pathak S, Kedia-Mokashi N, Saxena M, D’Souza R, Maitra A, Parte P, Gill-Sharma MK and Balasinor N. Effect of tamoxifen treatment on global and Insulin-like growth factor 2-H19 locus specific DNA methylation in rat spermatozoa and its association with embryo loss. Fertility & Sterility: 91, (Supplement): 2253-2263, 2009

  10. D’Souza R, Pathak S, Upadhyay R, Gaonkar R, D’Souza S, Sonawane S, Gill- Sharma M K and Balasinor N H. Disruption of tubulobulbar complex by high intratesticular estrogens leading to failed spermiation Endocrinology 150: 1861–1869, 2009

Present students

  • Ryan D’Souza
  • Shilpa Pathak
  • Neelam Mokashi
  • Rahul Upadhyay
  • Mandar Ankolkar

Past student

  • Ms Neelam Kedia

Projects (Extramural projects ongoing)

  • Role of imprinting cluster on rat chromosome 1 in embryogenesis (Funded by DBT)
  • Estrogen signaling in imprint acquisition/maintenance at the Igf2-H19 locus in male germ line (Funded by ICMR “Medical Innovation”)
  • Characterization of molecular events during spermiation (Funding Agency: DST)