Dr. Sadhana Gupta
Academic Background
- Ph.D , Biochemistry (Mumbai University,2008)
- M.Sc, Applied Biology (Mumbai University, 1999)
- B.Sc, Microbiology (Mumbai University, 1983)
Professional Experience
2018 – till date: Scientist C, National Institute for Research in Reproductive Health (NIRRH), Mumbai.
2015 to 2018: Scientist ‘B’, National Institute for Research in Reproductive Health (NIRRH), Mumbai.
2012 to 2015: Scientist ‘B’, Clinical division, National Institute of Nutrition (NIN), Hyderabad.
2010 to 2012: Technical Officer, Molecular and Cellular Biology, NIRRH.
1994 to 2009: Research Assistant, Molecular Immunology division, NIRRH.
Research Interests
- Pre-clinical Evaluation and Development of Microbicides
- Vaginal Mucosal Innate Immunity
- Reproductive tract Infections/Sexually transmitted Infections
- Early Detection and Prevention of Cervical cancer
- Immune responses in HPV-associated Cervical cancer
Awards & Achievements
- Received Best Scientific Research Award for the poster entitled “Correlation of Integrin Expression on Endometrial Cells and Peripheral Blood Lymphocytes to assess the Endometrial Function in Women” at the 18th National Symposium of Reproductive Biology and Comparative Endocrinology held at Chennai, December 27-29, 1999.
- Awarded full scholarship grants to present work at Microbicides 2006 Conference at Cape town, South Africa, Gordon Research Conference on Antimicrobial Peptides at Italy and XVII International AIDS 2008 Conference at Mexico.
Publications
Interaction of contraceptive antimicrobial peptide nisin with target cell membranes: implications for vaginal use as a microbicide
2009
Gupta SM, Aranha CC, D’Souza S, Bellare RJ and Reddy KVR
Contraception 80: 299-307, 2009
Assessment of cervicovaginal cytokine levels following exposure to microbicide Nisin gel in rabbits
2008
Aranha CL, Gupta SM and Reddy KVR
Cytokine 43: 63-70, 2008(IF: 2
Evaluation of developmental toxicity of microbicide Nisin in rats
2008
Gupta SM, Aranha CC and Reddy KVR
Food Chem Toxicol 46: 598-603, 2008
Toll-Like receptors and cytokines as surrogate biomarkers for evaluating vaginal immune response following microbicide administration
2008
Gupta SM, Aranha CC, Mohanty MC and Reddy KVR
Mediators Inflamm 23: 45-59, 2008
Contraceptive efficacy of antimicrobial peptide Nisin: In vitro and in vivo studies
2004
Aranha CC, Gupta S and Reddy KVR
Contraception 69 : 333-338, 2004
Evaluation of anti-microbial peptide Nisin as a safe vaginal contraceptive agent in rabbits: In vitro and in vivo studies
2004
Reddy KVR, Aranha C, Gupta SM and Yedery RD
Reproduction, 128 : 117-126, 2004
Expression of integrin receptors on peripheral lymphocytes : correlation with endometrial receptivity
2001
Reddy KVR, Gupta SM and Meherji PK
Am J Reprod Immunol 46 : 188-195, 2001
Lymphocytes- their possible endocrine role in the regulation of fertility
1996
Shahani SK, Gupta SM and Meherji PK
Am J Reprod Immunol 35: 1-4, 1996
Early pregnancy factor as a marker for assessing embryonic viability in threatened and missed abortions
1994
Shahani SK, Moniz CL, Bordekar AD, Gupta SM and Naik K
Gynaec Obstet Invest 37: 73-76, 1994
Demonstration of IgG Fc receptors on spermatozoa and their utilization for the detection of circulating immune complexes in human serum
1980
Witkin SS, Shahani SK, Gupta S, Good RA and Day NK
Clin Exp Immunol 41 : 441-452, 1980
Projects Ongoing
Evaluation of Biomarkers for Early detection of Cervical cancer in Indian Women.
